WCF Chapter 1, Of Holy Scripture, is the bedrock under the sermon's entire argument. The confession affirms that Scripture is the only sufficient, certain, and infallible rule of all saving knowledge, faith, and obedience, and that the Holy Spirit speaking in Scripture is the supreme judge by which all controversies of religion are to be determined. This is exactly what Paul means when he says the lawless one is killed by the breath of Christ's mouth. The Word is the weapon that exposes and destroys every false system, and it is also the inheritance every believer has been handed to stand firm.
WCF Chapter 3, Of God's Eternal Decree, and WCF Chapter 10, Of Effectual Calling, speak directly to Paul's anchor in verses 13-14. God chose you as firstfruits to be saved, through sanctification by the Spirit and belief in the truth. The confession grounds the believer's security not in the strength of their own faith but in the unchangeable decree and effectual call of God, who enlightens, renews, and draws his people irresistibly to himself. This is not intimidating theology; it is the most stable ground a shaken church can stand on.
The Reformers who first produced this confession explicitly connected the man of lawlessness passage to certain claims of the papacy, particularly the claim that the Pope functions as the vicar of Christ whose word is binding law. The confession does not pretend this is a settled exegetical certainty, but it takes seriously that Paul's warning is not merely abstract but has real targets in church history.